Mount Sinai Careers

POSTDOCTORAL FELLOW

New York, United States
Research


Job Description

The Mount Sinai Health System
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The Mount Sinai Health System’s commitment to excellence extends beyond delivering world-class health care. The System’s ongoing success is dependent upon our highly motivated, nonclinical professionals working to improve business operations. Our leadership team is driven to provide exceptional service by cultivating a workforce that is dedicated to upholding Mount Sinai’s mission of delivering innovative, breakthrough medicine with compassion and integrity.
 
Are you ready to discover the world of limitless possibilities that comes with wearing the badge? Explore more about this opportunity and how you can help us write a new chapter in our story of unrivaled patient care!
 
What You’ll Do:
A NIH-funded Postdoctoral Fellow position is now available for studying the fate of dividing human hematopoietic stem cells in the Tisch Cancer Institute, Division of Hematology/Medical Oncology at the Icahn School of Medicine at Mount Sinai Hospital.The applicant will be investigating molecular mechanisms of stem and progenitor cell fate specification using single cell analysis,transplantation into mouse models, gene expression profiling and analysis of chromatin structure. One focus of the lab is to understand how specialized hematopoietic stem cells are programmed to activate stem cell self-renewal rather than undergoing differentiation . A second focus is to understand how stem cells become specified along specific hematopoietic lineages. Projects will utilize recently developed novel tools to isolate and expand hematoipoetic stem cells and to study their cell fate specification and/or maturation through manipulation of gene expression in vitro and in vivo. Experimental approaches include classical cell and molecular biology techniques, small interfering RNA technologies, molecular profiling, chromatin immunoprecipitation (ChIP), genetic manipulation of mice, stem and progenitor cell culture, and transplantation into mice.
 
What You’ll Bring:
Qualifications:

The candidate is also expected to be highly self-motivated, creative and capable of contributing productively in a team environment. Excellent communication skills in written and oral English are essential. PhD in molecular and cellular hematopoiesis immunology or immunology related disciplines: Knowledge of basic and advanced cellular and molecular hematopoiesis and techniques that are required to pursue such studies.

Job Requirements:

Interested applicants should be highly motivated, have a PhD and/or MD degree, with research experience in the field of hematopoietic stem cell biology. Experience with hematopoietic cell culture, gene expression profiling, real-time quantitative PCR, western blotting and with mouse transplantation assays is highly desirable.

Effective written and verbal communication skills are required. Strong work ethic, creativity, and enthusiasm are required.
Do you share our dedication to extraordinary service and have what it takes to wear the badge? Apply now!
 
Who We Are:
Over 35,000 employees strong, the mission of the Mount Sinai Health System is to provide compassionate patient care with seamless coordination and to advance medicine through unrivaled education, research, and outreach in the many diverse communities we serve.
 
Formed in September 2013, The Mount Sinai Health System combines the excellence of the Icahn School of Medicine at Mount Sinai with seven premier hospital campuses, including Mount Sinai Beth Israel, Mount Sinai Beth Israel Brooklyn, The Mount Sinai Hospital, Mount Sinai Queens, Mount Sinai Roosevelt, Mount Sinai St. Luke’s, and New York Eye and Ear Infirmary of Mount Sinai.
 
The Mount Sinai Health System is committed to the tenets of diversity and workforce that are strengthened by the inclusion of and respect for our differences. We offer our employees a highly competitive compensation and benefits package, a 403(b) retirement plan, and much more.
 
The Mount Sinai Health System is an equal opportunity employer. We promote recognition and respect for individual and cultural differences, and we work to make our employees feel valued and appreciated, whatever their race, gender, background, or sexual orientation.
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