The Mount Sinai School of Medicine has a Post-Doctoral Fellow opening immediately available in the laboratory of Dr. Joshua Brody, Director, Lymphoma Immunotherapy Program. This individual will perform a wide variety of moderately complex laboratory tasks/experiments, and maintain lab equipment and inventory levels of supplies. Responsibilities of this position involve designing protocols and carrying out experiments, interpreting results, and preparing figures to convey analyses. Experimental duties will include but are not limited to performing cellular and molecular immunology techniques such as Flow Cytometry, ELISA, Luminex, and studies with animals as well as primary patient specimens. The lab will provide the chance to learn novel aspects of basic and tumor immunology, multi-parametric flow cytometry and phospho-flow signaling studies, animal techniques including bone marrow transplantation, anti-tumor vaccinations, and a large variety of functional assessments of anti-tumor T cell induction. Side projects include bioinformatic-based collaborations with colleagues tracking T-cell responses using high-throughput sequencing of the entire TCRbV repertoire and studies of small-molecule inhibitors of lymphocyte signal transduction, e.g. PI3K, mTOR, btk. Our lab has the rare opportunity to both perform correlative studies on primary patient tumor samples from early phase clinical trials and to continually develop advancements in those trials based on what is learned. The core mission is the translation of basic science in tumor immunology into novel and rapidly accruing clinical trials. Because the lab focuses on basic and applied tumor immunology (particularly in lymphoma, melanoma, and ovarian adenocarcinoma) there will be a high expectation for the Fellow to continually stay apprised of the literature as well as practical skill sets relevant to this field.
Ph.D. degree in sciences or relate field
3 years in a research environment
Microsoft Word, Excel, Powerpoint – Intermediate
Flow Cytometry Analysis Software – Intermediate
Excellent organizational, problem solving and analytical skills
Excellent verbal, written and interpersonal communication skills
Knowledge of standard research concepts