Employment Type: Full time, 1 year with the possibility to extend, start date of Spring 2019
The high-resolution exposomics section of the Senator Frank R. Lautenberg Environmental Health Sciences Laboratory in the Department of Environmental Medicine and Public Health at the Icahn School of Medicine at Mount Sinai seeks talented post-doctoral fellow applicants for positions that will involve untargeted profiling of endogenous and exogenous metabolites, nutrients and toxins in human tissues and other matrices. The position will provide assistance in LC-HRMS and GC-HRMS analysis in support of both research and service activities supporting precision medicine and exposome research. Projects include developing novel untargeted analysis techniques for various biological tissues and samples, development of samplers to assess exposures, establishing workflows for analyzing untargeted high-resolution mass spectrometry data and studies focused on environmental determinants of human disease. The facility currently houses one UHPLC-Orbitrap (Thermo Q-Exactive HFX) and one GC-Orbitrap (Thermo GC Q-Exactive), and has plans to strengthen its technology base further.
Responsibilities may include:
• Preparing and analyzing biological samples for analysis with LC-HRMS or GC-HRMS
• Development of methods for measuring exposure and disease biomarkers in human samples
• Perform sample analysis QA/QC
• Operating and maintaining GC or LC instrumentation
• Compound identification
• Performing OMICS data analysis.
• Bioinformatic workflows for data extraction, processing and annotation
Our laboratory is located on Central Park in New York City in the Icahn School of Medicine and is affiliated with the Mount Sinai Health System, the largest health care provider in New York. The Department of Environmental Medicine and Public Health has an NIEHS P30 core center with a pilot grant program to which fellows are eligible to apply and a formal mentoring and development program in conjunction with an NICHD-funded T32 training grant. The department also includes the new Institute for Exposomic Research, the first in the world focused on exposomics. The team science approach in this department provides opportunities to co-author publications with leading collaborators. Fellows will be offered subsidized housing in Manhattan and a competitive stipend. Base salary is comparable to NIH stipend rate for each year of experience: https://grants.nih.gov/grants/guide/notice-files/NOT-OD-16-131.html. Work related experience will be considered in determining level and salary.