Ground breaking science. Advancing medicine. Healing made personal.
Roles & Responsibilities:
The Associate Researcher is an entry laboratory
research position, responsible for conduct of routine and assisting in routine
and standardized experiments using techniques specific to the assigned research
project under the supervision of the Principal Investigator or a senior researcher.
This individual typically conducts laboratory research and the position may
include lab and clerical support. S/he analyzes and assists in interpreting
Our research focuses on identifying the epigenetic basis of neurodegenerative and psychiatric disorders. We study how miRNAs and histone modifying enzymes contribute to the establishment and maintenance of neuronal identity and specialized functions. We are particularly interested in understanding the epigenetic mechanisms of cellular plasticity and its role in regulation of microglia-neuron communication. One of the major focuses of our research lies in the development of animal models of human neurological disease associated with abnormal function of epigenetic regulators of different types. Using pioneering technologies including cell type specific analysis of mRNAs, miRNAs and chromatin modifications in neurons in vivo, our research aims at understanding the mechanism of neurological disorders and at their potential treatment by targeting the neuronal epigenome.
- Individual will oversee daily operations of the lab including placing lab orders, coordinating collaborations with other institutions, overseeing lab safety and filing necessary documentation, coordinating maintenance of equipment and lab space, and generally maintaining an organized lab
- Furthermore, the individual will be responsible to maintain transgenic mouse lines, perform mouse behavior and help doing mouse surgeries
- In addition to these baseline tasks, the individual will have the opportunity to become proficient in both in vitro and in vivo techniques, including primary neuronal culture, Western blotting, RNA extraction, qPCR, genotyping, immunofluorescence, behavioral assays, profusions, etc.
- Particularly motivated individuals will also have the opportunity to conduct their own research project and to learn more advanced molecular techniques, such as HITS-CLIP, ChIP, ATAC-seq, TRAP, RNA-seq, and CRISPR
- Other duties as assigned
- Education: Bachelor’s degree in Biology, Biochemistry or Neuroscience or related field required
- Experience: Prior research/laboratory experience, prior mouse handling experience, appropriate verbal, written and interpersonal skills, and organizational, problem solving and analytical skills
- Commitment: 2 years
- We are looking for a highly motivated young researcher interested in neuroepigenetics who likes to work in a great team and who is committed and passionate about science
Strength Through Diversity
The Mount Sinai Health System believes that diversity is a driver for excellence. We share a common devotion to delivering exceptional patient care. Yet we’re as diverse as the city we call home- culturally, ethically, in outlook and lifestyle. When you join us, you become a part of Mount Sinai’s unrivaled record of achievement, education and advancement as we revolutionize medicine together.
We work hard to acquire and retain the best people, and to create a welcoming, nurturing work environment where you can develop professionally. We share the belief that all employees, regardless of job title or expertise, can make an impact on quality patient care.
Explore more about this opportunity and how you can help us write a new chapter in our story!
Over 38,000 employees strong, the mission of the Mount Sinai Health System is to provide compassionate patient care with seamless coordination and to advance medicine through unrivaled education, research, and outreach in the many diverse communities we serve.
Formed in September 2013, The Mount Sinai Health System combines the excellence of the Icahn School of Medicine at Mount Sinai with seven premier hospital campuses, including Mount Sinai Beth Israel, Mount Sinai Beth Israel Brooklyn, The Mount Sinai Hospital, Mount Sinai Queens, Mount Sinai West (formerly Mount Sinai Roosevelt), Mount Sinai St. Luke’s, and New York Eye and Ear Infirmary of Mount Sinai.
The Mount Sinai Health System is an equal opportunity employer. We promote recognition and respect for individual and cultural differences, and we work to make our employees feel valued and appreciated, whatever their race, gender, background, or sexual orientation.