Mount Sinai Careers

POSTDOCTORAL FELLOW

New York, New York
Research


Job Description

The Center for Advanced Circuit Therapeutics (C-ACT) at The Icahn School of Medicine at
Mount Sinai is seeking a Postdoctoral Fellow to perform quantitative analyses of structural,
diusion and functional brain images. Specic projects include preprocessing of resting-
state functional MRI and diusion-weighted images, functional and structural connectivity
analyses, and image segmentation and quantitative volumetrics. Projects involve devel-
opment and implementation of treatment selection biomarkers, individualized multimodal
surgical targeting methods, longitudinal outcome metrics across a wide range of neuropsy-
chiatric disorders including Depression, OCD, Movement Disorders, and Epilepsy. This is
an excellent opportunity to participate in cutting-edge imaging research as a member of a
multidisciplinary research team of technical and clinical experts with access to state-of-the-
art imaging equipment.
This individual will be jointly supervised by Dr. Ki Sueng Choi, imaging leader at C-ACT,
and Dr. Helen Mayberg, Director at C-ACT, and will have the opportunity to interact with
a diverse team of investigators with complementary expertise in neuroimaging, psychiatry,
neurology, neurosurgery, neuroengineering, computational neuroscience, and bioinformat-
ics. Anticipated start date is March 11, 2019.
The Center for Advanced Circuit Therapeutics (C-ACT) is a new centralized research unit,
imbedded within the Clinical Center for Neuromodulation to be based at Mount Sinai West
in June 2018. The Center supports research activities using imaging, invasive and noninva-
sive electrophysiology, performance and behavioral metrics, computational modeling, and
clinical and research bioinformatics involving surgical neuromodulation patients. This core
facility will enable development and testing of new brain-tuning strategies to accelerate
the delivery of state-of-the-art individualized care for patients with advanced neuropsychi-
atric disordersbe it those where brain stimulation therapies are already clinically available,
such as Parkinsons disease and epilepsy, or more experimental applications such as depres-
sion, OCD, eating disorders, and addiction. Development and testing of next-generation
implantable devices, computation-based algorithms for treatment delivery, and clinical pi-
loting of novel applications will complement ongoing evidenced-based care for established
uses of DBS and other neuromodulation strategies.

Specic tasks will include:
Development of image analysis protocols and methods for brain MRI and PET (anatomical
imaging, diffusion MRI, and functional MRI).
Development of multimodal statistical brain network analysis methods
Data analysis, interpretation and presentation using already existing image analysis software
packages or new using methods
Extraction of quantitative imaging biomarkers for psychiatric and neurological brain disorders
Writing of manuscripts, conference presentations, contribution to grant applications, and
mentorship of students.
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