Ground breaking science. Advancing medicine. Healing made personal.
The applicant will perform studies related to opioid drug addiction. It is estimated that ~125 people die each day in the U.S. due to opiate overdose which is now the second leading cause of accidental death among adults aged 15–64 years. The susceptibility to opiate addiction is at least in part determined by epigenetic regulation; therefore, knowledge about the epigenetic landscape in the brain of human addicts (which currently remains limited) is critical for the development of novel more efficacious treatments. The applicant will work on the project that aims to fill this void in knowledge by creating comprehensive genome-wide and cell-type-specific epigenetic maps in the brains of heroin addicts and in non-addicted individuals.
Duties and Responsibilities:
- Performing nuclei isolation from postmortem brain tissues
- RNA and DNA extraction from postmortem brain tissues
- Preparing sequencing libraries for whole-genome DNA methylation assays (BS/OxBS)
- Preparing sequencing libraries for histone modification assays (ChIP-seq)
- Maintain lab records/reports, supplies and reagents
- Performs other related duties
- Bachelor in science or a similar degree
- At least 6 months or more in research environment
- Computer and General Skills:
- MS Word – Basic; Excel – Basic
- Ability to write reports in English
The Mount Sinai Health System believes that diversity is a driver for excellence. We share a common devotion to delivering exceptional patient care. Yet we’re as diverse as the city we call home- culturally, ethically, in outlook and lifestyle. When you join us, you become a part of Mount Sinai’s unrivaled record of achievement, education and advancement as we revolutionize medicine together.
We work hard to acquire and retain the best people, and to create a welcoming, nurturing work environment where you can develop professionally. We share the belief that all employees, regardless of job title or expertise, can make an impact on quality patient care.
Explore more about this opportunity and how you can help us write a new chapter in our story!
Over 38,000 employees strong, the mission of the Mount Sinai Health System is to provide compassionate patient care with seamless coordination and to advance medicine through unrivaled education, research, and outreach in the many diverse communities we serve.
Formed in September 2013, The Mount Sinai Health System combines the excellence of the Icahn School of Medicine at Mount Sinai with seven premier hospital campuses, including Mount Sinai Beth Israel, Mount Sinai Beth Israel Brooklyn, The Mount Sinai Hospital, Mount Sinai Queens, Mount Sinai West (formerly Mount Sinai Roosevelt), Mount Sinai St. Luke’s, and New York Eye and Ear Infirmary of Mount Sinai.
The Mount Sinai Health System is an equal opportunity employer. We promote recognition and respect for individual and cultural differences, and we work to make our employees feel valued and appreciated, whatever their race, gender, background, or sexual orientation.