POSTDOCTORAL FELLOW

Job Description

The Translational and Molecular Imaging Institute (TMII) at The Icahn School of Medicine at Mount Sinai is seeking an Postdoctoral Fellow to work on a highly innovative NIH/NHLBI funded Program Project Grant P01HL131478, entitled “Stress and Atherosclerotic Plaque Macrophages – a Systems Biology Approach”, PI: Zahi A. Fayad. The goals of this 5-year project are (i) to provide mechanistic insights on how stress biologically affects macrophage dynamics, using mouse models of atherosclerosis; (ii) to develop translational imaging technologies that allow monitoring macrophage dynamics non-invasively in animal models and humans; and (iii) to employ the developed neuroimaging and cardiovascular technologies (MR/PET) to study how post-traumatic stress disorder (PTSD) leads to atherosclerosis in humans. 


Specific tasks will include:
• Development of image analysis protocols and methods for brain and vascular MRI and PET acquired on the Siemens Biograph mMR PET/MRI scanner 
• Data analysis, interpretation and presentation using existing image analysis software packages or new methods
• Other projects include evaluation of anti-inflammatory nanotherapy in a mouse model of atherosclerosis, conducting in vivo experiments, assisting in the acquisition of in vivo imaging data on preclinical scanners, as well as in the ex vivo processing, including flow cytometry and histology of tissues,
• Writing of manuscripts and grant proposals
• Working with research administrators in organizing study protocols, and ensure compliance 
• Perform other related duties as required

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