Ground breaking science. Advancing medicine. Healing made personal.
Scientist is experienced in the conduct of research involving the understanding
of human diseases and improvement of human health. May assist in the operation
of the clinical laboratory. Engages in clinical investigation or other
research, production, technical writing, and related activities, and may mentor
less senior scientist and Associate Researcher staff.
The research project in the laboratory will study antigen-specific B lymphocyte responses in human food allergy. The project aims to understand how specific IgE and IgG repertoires change in conditions of active allergic disease and after spontaneously acquired or immunotherapy induced tolerance.
The candidate's responsibilities will include: standardizing methods for the analysis of overall gene expression as well as B cell repertoires at the single cell level and through bulk RNA sequencing of purified B cell populations; apply this analysis to identify differences in B cell phenotype and allergen binding affinities in conditions of allergy and tolerance. The candidate will also prepare results and conclusions for presentation in scientific meetings and publication in a scientific journal. The work will require active interaction and collaborations with other lab members and clinical collaborators. There will be participation in weekly group lab meetings and Journal Club and assistance with manuscript and grant writing, as well as mentoring of students.
- Conducts research to develop methodologies, instrumentation and procedures for medical application, analyzing data and presenting findings.
- Designs and conducts complex clinical research studies requiring the determination and evaluation of alternative methods, computational modeling, diagnosis and treatment.
- Plans and directs studies to investigate human or animal disease, preventive methods, and treatments for disease.
- May assist in clinical laboratory operations.
- Follows strict safety procedures when handling materials to avoid contamination.
- Teaches principles of medicine and medical and laboratory procedures to physicians, residents, students, and research staff.
- Confers with health departments, industry personnel, physicians, and others to develop health safety standards and public health improvement programs.
- Develops treatments and designs research tools and techniques.
- Explores subject area and defines scope and selection of problems for investigation through conceptually related studies
- Develops hypotheses to be tested and methodology for evaluating results.
- Examines the results of clinical trials and adjusts the dosage levels to reduce negative side effects or to induce better results.
- Communicates research results to the scientific community via published papers.
- Develops new proposals for research and obtain support for new and/ or continuing research activities.
- Makes recommendations that have a major impact on extensive scientific research activities.
- Performs other related duties.
- PhD in Biological Science or related field
- 3 years’ experience
- Ability to work independently or as part of a team and be able to communicate clearly and concisely, both orally and in writing.
- Exceptional attention to detail and accuracy
The Mount Sinai Health System believes that diversity is a driver for excellence. We share a common devotion to delivering exceptional patient care. Yet we’re as diverse as the city we call home- culturally, ethically, in outlook and lifestyle. When you join us, you become a part of Mount Sinai’s unrivaled record of achievement, education and advancement as we revolutionize medicine together.
We work hard to acquire and retain the best people, and to create a welcoming, nurturing work environment where you can develop professionally. We share the belief that all employees, regardless of job title or expertise, can make an impact on quality patient care.
Explore more about this opportunity and how you can help us write a new chapter in our story!
Over 38,000 employees strong, the mission of the Mount Sinai Health System is to provide compassionate patient care with seamless coordination and to advance medicine through unrivaled education, research, and outreach in the many diverse communities we serve.
Formed in September 2013, The Mount Sinai Health System combines the excellence of the Icahn School of Medicine at Mount Sinai with seven premier hospital campuses, including Mount Sinai Beth Israel, Mount Sinai Beth Israel Brooklyn, The Mount Sinai Hospital, Mount Sinai Queens, Mount Sinai West (formerly Mount Sinai Roosevelt), Mount Sinai St. Luke’s, and New York Eye and Ear Infirmary of Mount Sinai.
The Mount Sinai Health System is an equal opportunity employer. We promote recognition and respect for individual and cultural differences, and we work to make our employees feel valued and appreciated, whatever their race, gender, background, or sexual orientation.