Ground breaking science. Advancing medicine. Healing made personal.
Amaia Lujambio´s research group studies mechanisms of liver cancer initiation and liver cancer maintenance. In particular, we are interested in how genetic alterations in cancer cells contribute to tumorigenesis, alter treatment response, and create vulnerabilities that may be targeted therapeutically. Our research interests involve the establishment of in vitro and in vivo systems for the study of liver cancer, as well as the rational use of shRNA and CRISPR libraries to identify drug targets for the disease. We utilize sophisticated mouse models of cancer, RNAi technology, valuable human cancer samples, and genetic and epigenetic profiling as key tools. The ultimate goal is to improve our understanding of aging and liver cancer, and to identify novel strategies that can be exploited therapeutically to improve healthspan and longevity.
We are accepting applications from talented and enthusiastic candidates who are interested in a dynamic, well-supported lab at a top research institution. The project will involve performing CRISPR screens to identify novel drug targets for liver cancer and performing in vivo experiments to validate novel therapies in personalized mouse models of HCC
- Bachelor’s degree in life sciences from an accredited institution
- Experience with cell culture and mouse work, and basic molecular biology techniques is required
- Bioinformatics experience is a plus
- The candidate will be expected to work well in a collaborative environment and with little supervision
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