Strength Through Diversity
Ground breaking science. Advancing medicine. Healing made personal.
Roles & Responsibilities:
- This Postdoctoral Fellow position is in the Division of Allergy and Immunology, Department of Pediatrics. The Postdoctoral Fellow will in conjunction with the Principal Investigator (Mirna Chehade, MD, MPH) at the Mount Sinai Center for Eosinophilic Disorders (MSCED), investigating the immunopathology of eosinophilic esophagitis (EoE).
We are seeking a highly motivated individual to work in the field of eosinophilic gastrointestinal disorders. The successful candidate will participate in a research project focused on the effect of proton pump inhibitors (PPI’s) on the esophageal transcriptome in EoE subtypes, and the role of various immune and signaling pathways in PPI-mediated suppression of esophageal eosinophilia. The candidate will be participating in an exciting journey integrating in silico and wet Lab approaches to establish a new paradigm for translating gene expression profiles into mechanistic insights and eventually personalized precision patient care. In silico approaches including analyses of NGS data (including genome wide association studies, RNA sequencing (single cell and whole tissue)), bioinformatics strategies to study the genetic basis of EoE, and wet Lab assays including molecular analyses of primary esophageal cell culture systems, will be conducted.
Requirements: *PhD or equivalent degree with a background knowledge in immunology. *Working knowledge of principles of immunology and molecular biology is required. *Competency in RNA isolation from tissue/cells, RNAseq analysis and immunohistochemistry, as well as demonstrated experience in cell culture techniques, qRT-PCR, cytokine assays and flow cytometry.
Strength Through Diversity
The Mount Sinai Health System believes that diversity and inclusion is a driver for excellence. We share a common devotion to delivering exceptional patient care. Yet we’re as diverse as the city we call home- culturally, ethically, in outlook and lifestyle. When you join us, you become a part of Mount Sinai’s unrivaled record of achievement, education and advancement as we revolutionize healthcare delivery together.
We work hard to recruit and retain the best people, and to create a welcoming, nurturing work environment where you have the opportunity and support to develop professionally. We share the belief that all employees, regardless of job title or expertise, have an impact on quality patient care.
Explore more about this opportunity and how you can help us write a new chapter in our story!
Who We Are
Over 38,000 employees strong, the mission of the Mount Sinai Health System is to provide compassionate patient care with seamless coordination and to advance medicine through unrivaled education, research, and outreach in the many diverse communities we serve.
Formed in September 2013, The Mount Sinai Health System combines the excellence of the Icahn School of Medicine at Mount Sinai with seven premier hospitals, including Mount Sinai Beth Israel, Mount Sinai Brooklyn, The Mount Sinai Hospital, Mount Sinai Queens, Mount Sinai West (formerly Mount Sinai Roosevelt), Mount Sinai St. Luke’s, and New York Eye and Ear Infirmary of Mount Sinai.
The Mount Sinai Health System is an equal opportunity employer. We promote recognition and respect for individual and cultural differences, and we work to make our employees feel valued and appreciated, whatever their race, gender, background, or sexual orientation.