Associate Researcher I (Guccione Lab), Oncological Sciences

Job Description

Strength Through Diversity

Ground breaking science. Advancing medicine. Healing made personal.

Roles & Responsibilities:

The Guccione lab has a long-standing interest in understanding basic mechanisms of transcriptional and post-transcriptional regulation in order to identify therapeutic opportunities in oncology.

Duties and Responsibilities
  • Lab Duties
    • Coordinates and takes responsibility for basic lab duties. Assists with the ordering and tracking of laboratory supplies. Performs routine technical tasks, and assists in the general maintenance of the lab (i.e. stock reagents and maintain inventory of the labs supplies)
    • Has oversight of recombinant DNA work, protein biochemistry and cell culture. Under supervision (or independently), will participate in standard lab experiments (i.e. Sterile cell culture (primary cells, 3D organoids)
      • PCR, cloning recombinant DNA, basic molecular biology methods
      • Immunohistochemistry, ELISA
      • Flow cytometry (FACS)
      • Protein biochemistry such as Purification, Western blotting and IP)
  • Mouse colony management including handling, breeding and mice genotyping (experience with mouse surgery and/or models of cancer is strongly preferred)
  • Has oversight of mouse colony (including mouse models of cancer). Participates actively in developing, recommending and implementing new approved procedures, or modifications to existing protocols and procedures. Handles IACUC/IBC/IRB protocol submission
  • Maintains and updates technical knowledge
  • Communication/Relationship with Others
    • Cooperates, communicates and relates well to all members of the lab. Effective oral and written communication skills
  • Participates and performs other related duties as required
  • Bachelor’s degree in life sciences
  • 2 years of experience in bench research
  • Mouse experience required
Strength Through Diversity

The Mount Sinai Health System believes that diversity is a driver for excellence. We share a common devotion to delivering exceptional patient care. Yet we’re as diverse as the city we call home- culturally, ethically, in outlook and lifestyle. When you join us, you become a part of Mount Sinai’s unrivaled record of achievement, education and advancement as we revolutionize medicine together.


We work hard to acquire and retain the best people, and to create a welcoming, nurturing work environment where you can develop professionally. We share the belief that all employees, regardless of job title or expertise, can make an impact on quality patient care.


Explore more about this opportunity and how you can help us write a new chapter in our story!

Who We Are

Over 38,000 employees strong, the mission of the Mount Sinai Health System is to provide compassionate patient care with seamless coordination and to advance medicine through unrivaled education, research, and outreach in the many diverse communities we serve.


Formed in September 2013, The Mount Sinai Health System combines the excellence of the Icahn School of Medicine at Mount Sinai with seven premier hospital campuses, including Mount Sinai Beth Israel, Mount Sinai Beth Israel Brooklyn, The Mount Sinai Hospital, Mount Sinai Queens, Mount Sinai West (formerly Mount Sinai Roosevelt), Mount Sinai St. Luke’s, and New York Eye and Ear Infirmary of Mount Sinai.


The Mount Sinai Health System is an equal opportunity employer. We promote recognition and respect for individual and cultural differences, and we work to make our employees feel valued and appreciated, whatever their race, gender, background, or sexual orientation. 


EOE Minorities/Women/Disabled/Veterans

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