Strength Through Diversity
Ground breaking science. Advancing medicine. Healing made personal.
- Applications are invited for a postdoctoral research associate position in the Department of Neurology at the Icahn School of Medicine in New York City. The successful candidate will work in the laboratory of Dr. Helen Mayberg, MD studying the longitudinal effects of subcallosal cingulate deep brain stimulation for treatment-resistant depression on the power spectrum of the resting electroencephalogram (EEG).
Deep brain stimulation of subcallosal cingulate white matter (scDBS) is a promising therapy for patients with treatment resistant depression (TRD). It is believed that these patients suffer from a system level disorder, affecting more than a single neurotransmitter or brain region, but a complex network of systems and pathways linking cortical, subcortical, and limbic sites, as well as the neurotransmitters and molecular mediators potentially involved.
Our research program aims to identify biomarkers in the EEG activity that could be used to predict which patients are most likely to respond to scDBS. Due to the invasive nature of scDBS therapy it is important to reduce the number of patients that will be exposed unnecessarily to the risks inherent in brain surgery and electrode implantation. We hope to use this knowledge to create prognostic models that predict how cognitive ability will change with time after stimulation, track spontaneous and intervened recovery and inform further interventions such as re-implantation of electrodes.
- Required: PhD/doctorate in computational biology, mathematics, cognitive neuroscience or related disciplines.
Solid background in EEG.
Expertise in statistical methods and analysis of neuroimaging data.
Evidence of published peer-reviewed research
Strong analytical, quantitative, and programming skills
Proven ability to work independently
Excellent skills in written and spoken English Preferred: Experience with Matlab and/or Python
Experience in designing and conducting experiments in cognitive neuroscience
Experience with clinical research
The initial term is for two years.