Description
Roles & Responsibilities:
The Gregorio Lab in the Cardiovascular Research Institute (CVRI) at the Icahn School of Medicine at Mount Sinai is seeking highly motivated candidates for the full-time position of Postdoctoral Research Associate I. Dr. Gregorio’s NIH-funded research incorporates molecular, cellular and physiological approaches on the RNA/protein level to identify molecular mechanisms that underlie contractile protein function in heart and skeletal muscle diseases. Current studies focus on the role of RNA-binding proteins in muscle function that are altered during normal development and in disease such as Duchenne Muscular Dystrophy. The laboratory generates, analyzes, and integrates high-throughput fluorescence imaging, molecular biology and biochemistry to determine the mechanism of RNA binding proteins in cells (e.g., iPSCs, primary myocytes) and animal models that reflect patho/physiological states. The successful Postdoctoral candidate will possess a cell/molecular skill set with an emphasis on RNA biology appropriate to accomplish the lab’s goals. In addition, they will possess the drive required to research complex disease and will be able to work independently as well as collaboratively. CVRI is dedicated to training the next generation of scientists, and the Postdoctoral candidate will benefit from the interdisciplinary environment.
Duties:
· Lead a research project in close collaboration with the PI and other lab members.
· Innovate new areas of experimental inquiry.
· Advance technical aspects of experimental approaches and mechanistic understanding of biological problem.
· Mentor junior lab members and contribute to a productive scientific environment.
· Maintain detailed records and disseminate research findings in meetings and as manuscripts in scientific journals: strong writing skills are essential
· Apply for independent funding and contribute to grant proposals submitted by the PI.
· There may be additional duties assigned as it relates to this position.
Requirements:
Minimum Requirements:
· MD or PhD in biochemistry, molecular or cellular biology, physiology, biotechnology, biomedical engineering, or related field by time of hire.
· Documented ability to conduct original research.
· Ability to write manuscripts and grants proposals.
· Ability to work with small animals.
Preferred Qualifications:
*Experience with recombinant proteins, muscle proteins, and handling/dissection of small rodents. *Experience with enzyme kinetics/biochemical assays of protein-protein interactions. *Experience with fluorescence microscopy. *Experience with Duchenne Muscular Dystrophy Models. *Expertise in cardiac and skeletal muscle biology, post-transcriptional and translational regulation in heart and skeletal muscle disease pathology. *Experience in computational biology.
Responsibilities
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Qualifications
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Employer Description
Strength through Unity and Inclusion
The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.
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About the Mount Sinai Health System:
Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.
Equal Opportunity Employer
The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.
Compensation
The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $72500 - $80000 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.