Job Description

The laboratory of Silvia De Rubeis, PhD, at the Seaver Autism Center for Research and Treatment in the Department of Psychiatry at the Icahn School of Medicine at Mount Sinai in New York, is seeking an ambitious, creative, and motivated postdoctoral fellow with expertise in neuroscience to study the mechanisms underlying intellectual disability (ID) and autism spectrum disorder (ASD).

Dr. De Rubeis’ laboratory aims at translating emerging genetic findings from large-scale genomic studies into functional analyses in cellular and mouse models with the goal of understanding the pathogenic underpinnings of ID and ASD. The laboratory focuses on two rare
genetic disorders, DDX3X syndrome and ADNP syndrome, using cellular and animal models.
The laboratory currently comprises a postdoctoral fellow, two research associates, and an intern. 

To learn more about our scientific interests, please see our publications:

Qualifications and Experience

Basic qualifications:

·       PhD, MD, MD/PhD in Neuroscience/Molecular Biology/Cellular Biology;

·       Demonstrated expertise in neuroscience;

·       Strong record of publications in peer-reviewed journals;

·       Excellent communication skills;

·       Ability to work in an international and interdisciplinary team.

Preferred qualifications:

·       Prior experience with mouse models;

·       Experience with in utero manipulation techniques and/or stem cells biology;

·       Good understanding of genetics;

·       Familiarity with R and other statistical software.

We offer a 2-year position, renewable up to 5 years, with a competitive salary and benefit package. The candidate will have the opportunity to:

• Conduct cutting-edge research with a strong translational impact for neurodevelopmental disorders;
• Integrate the neuroscience expertise with genetics and genomics skills and be involved in large-scale genomic studies;
• Be an active participant in the vibrant and exciting research community of the Seaver Center and the Icahn School of Medicine at Mount Sinai. 

The Icahn School of Medicine at Mount Sinai offers convenient housing options for postdoctoral fellows. Postdocs also receive support from a dedicated Office of Postdoctoral Affairs. To learn more about postdoc services and resources, please visit:

The Seaver Autism Center for Research and Treatment at the Mount Sinai Health System is a fully integrated translational research center dedicated to discovering the biological causes of autism and developing breakthrough treatments. Our mission is to bridge the gap between new discoveries at the basic science level and clinical care, by developing new and improved
approaches to autism diagnosis and treatment. Our interdisciplinary patient-based research team includes psychiatrists, psychologists, a developmental pediatrician, neurologist, clinical geneticist, and trainees in medicine and psychology. The Seaver Autism Center is committed to
serving individuals of all levels of functioning and takes a unique genetics-first approach to ASD research. The Seaver Center is one of the highest ranked autism research centers and Investigators at the Seaver Center have strong collaborations with the Departments of Psychiatry, Neuroscience, and Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai. We also collaborate with several other institutions, nationally and internationally.

To learn more about the Seaver Autism Center, please visit:
To learn more about the Department of Psychiatry, please visit:
To learn more about the Mount Sinai Health System, please visit:


Please send a cover letter detailing your research interests, CV, and three references (include contact information) to Dr. De Rubeis at

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